Tsz was born in the early 1990s in British colonial Hong Kong and grew up there during the post-colonial period. She moved to Texas at the age of 13 and later attended The University of Texas at Austin, where she earned a BFA in Studio Art in 2015. While studying at UT, Kam met Nat Power, with whom she later formed the art duo Big Chicken & Baby Bird.

Tsz is a queer artist based in Austin. Her work explores gender and cultural identity through surrealist imagery, patterns, and decorative art. She also occasionally writes about her work, reflecting on the ideas and experiences that inform her artistic practice.